Chinese scientists develop non-hallucinogenic antidepressant

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Chinese scientists have designed two new compounds that could relieve depression. But it does not cause unwanted hallucinations.Scientists from the Center for Excellence in Molecular Cell Science under the Chinese Academy of Sciences (CAS) and ShanghaiTech University have mapped the crystal structure of psilocybin, an FDA-approved antidepressant, when it binds to the receptor. in the brain called serotonin 2A.

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Then the binding point of alxyloxibin and its receptor was previously unknown. Additional studies have found that the new binding, which is regulated by lipids and serotonin, is linked to a non-hallucinogenic antidepressant pathway, according to a study published Friday in the journal Science.

from the molecular pathway Researchers have devised two new compounds that primarily act on the newly discovered adhesion.In the mouse model test The high content of the compound will not cause the head-twitch behavior. which has long been seen as an indicator of hallucinations. And it also maintains a similar sedative effect to hallucinogens, according to the study.